Fenbendazole, An Anti Tumor Medication That Is Suitable For Humans
Fenbendazole is an anthelmintic medication that has been around since 1970 and it was primarily used for treating worm infections caused by parasites.
But recently, numerous peer-reviewed papers and publications have come out to prove the effectiveness of fenbendazole in treating different tumors in humans. Fenbendazole has been believed to help fight cancer through the characteristics described below.
As previously mentioned that several scientific reports and publications have provided evidence on the effectiveness of fenbendazole in the aggressive treatment of tumors in humans.
According to reports, the use of fenbendazole can effectively inhibit the development of tumors in cancer patients having large B-cell lymphoma, renal cell carcinoma, bladder cancer, and metastatic cancer.
Apart from this, the use of fenbendazole is very safe with little or no side effects.
It can be easily gotten without a prescription at retail stores all over the country.
Its cost of production is relatively cheap.
However, from our previous report on how fenbendazole works, It was indicated that the anti-tumor activities of fenbendazole are similar to that of the taxane groups used for chemotherapy. Also, fenbendazole has very low toxicity compared to other medications used for chemotherapy as a result of its outstanding profile and unique actions in the body.
According to several research and discoveries, it is quite obvious that parasites, viruses, and many more are the cause of most cancers in the human body.
As a matter of fact, we are hardly aware of many of these cases, particularly in a situation where the tumor cells live in an environment with unimpeded growth, usually caused by certain genetic traits and compromised immunity.
So, the use of anti-worm, anti-parasite, and anti-lactate medications are usually considered when carrying out an extensive chemotherapy or cancer treatment approach together with conventional tumor therapies.
Use of fenbendazole in humans
Fenbendazole is not primarily used by humans like mebendazole, It is a medication originally used for animals (mostly mammals, fishes, and birds) for the treatment of different kinds of parasitic infections and worms like roundworm, tapeworm, hookworm, and whipworms.
Fenbendazole became very popular through its sale under brand names like Safe-Guard or Panacur. We discovered its effectiveness in the treatment of cancer after carrying out a couple of research. Recently, this wonder drug came under our radar once again after a man suffering from small cell lung cancer became cancer-free using this worm expelling medication.
From that moment, the man created and dedicated a Facebook group and a website that would be used to record and narrate his experience and that of other patients suffering from similar conditions. According to his reports, fenbendazole is very effective for the treatment of different types of cancers like colorectal cancer, melanoma, prostate cancer, stage four pancreatic cancer, non-small lung cancer, and many more.
These new reports have been beneficial in establishing this fact and providing scientific proof about the activities and use of different types of benzimidazole compounds for the treatment of tumors in humans. In light of this, we can solidly confirm that both mebendazole and fenbendazole come with compounds that can be used to fight against tumors in the human body.
As a matter of fact, a couple of reports provided evidence that fenbendazole is more effective than mebendazole when it comes to cancer treatment. For instance, a study revealed that fenbendazole was more effective against Cryptococcus neoformans (a fungus that lives in an environment throughout the world and is responsible for Cryptococcus meningitis in humans) than mebendazole and other medications. Most of the reports published by scientists have revealed that fenbendazole contains cancer-fighting compounds. Additionally, this research paper indicated that the ability of fenbendazole to inhibit the growth of cancer cells which eventually leads to their death occurs through the modulation of several cellular pathways and has helped to establish this fact.
Combining this result with our earlier conclusion reveals that fenbendazole acts as a microtubule destabilizing agent that comes with an anti-neoplastic ability which can cause cancer death by modulating several multiple cellular pathways and can therefore be considered as a possible therapeutic agent.
According to the authors of the report, the microtubule depolymerization activity exhibited by fenbendazole towards cancer cells in humans occurs through the disruption of microtubule dynamics and blockage of glucose uptake in cancer cells by inhibiting the regulation of GLUT transporters which eventually starves the cancer cells. The expression of GLUT 4 (glucose transporter isoform 4) is reduced by fenbendazole. The uptake of glucose in cells is stimulated through insulin to move GLUT4 along the intracellular vesicles to the plasma membrane, causing glucose absorption. Fenbendazole is used to disrupt this movement through the microtubule which significantly limits the uptake of sugar stimulated by insulin.
Even though fenbendazole for humans interacts with a site on tubulin, just like colchicine, it is very different from other vinca alkaloids as it cannot be used as a standalone substitute for chemotherapy. Rather, just like many other compounds in the benzimidazole group, fenbendazole can be used to improve the anti-tumor effects of any chemotherapeutic option such as radiotherapy, surgery, berberine, sodium dichloroacetate (DCA), and so on.
Additionally, a newly published scientific report indicated that the genome p53 can be reactivated by fenbendazole and other similar medications. P53 genome is a cancer suppressor gene that stops the formation of tumors. It is popularly known as the Guardian of Genome. Its tumor suppressing ability can help fight some cancers.
Is Fenbendazole ideal for human consumption?
Primarily, fenbendazole is an anthelmintic medication used for treating parasitic worms in most animals. However, according to a study report by the European Medicine Agency, consuming fenbendazole orally in humans seems to be well tolerated (a single dose orally for 2000 mg/per individual and 500 mg/per individual for 10 days consecutively).
However, there is no scientific report on the effect associated with long time exposure to the medication. This can be linked to the ability of the drug to eliminate infections within two weeks or less.
Nevertheless, several individuals have consumed fenbendazole every day for several years as a cancer treatment or to prevent the reoccurrence of cancer. There are rare cases of side effects as the medications seem completely safe.
For more information check out: https://www.fenbendazole.org/